HP-1 Gamma mouse Monoclonal Antibody(3B9), 50ul Human Genome Knockout Libraries Increased expression of this gene

Increased expression of this gene is associated with colorectal cancer

This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription

CSNK1G1 (casein kinase 1 gamma 1) encodes a member of the casein kinase I gene family

The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1| MAPKK4) in vitro| and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells

suggesting a function in tumor invasion

HP-1 Gamma mouse Monoclonal Antibody(3B9), 50ul Human Genome Knockout Libraries Increased expression of this geneAt the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds