ITK Polyclonal Antibody, 50ul Cell fragmentation and collection USP45 differs from other USPs

USP45 differs from other USPs in that it contains a UBP-type zinc finger

The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers

GO annotations related to this gene include nucleic acid binding and damaged DNA binding

The erythroid-specific protein encoded by this gene| and the ubiquitous transcription factor CP2| form the stage selector protein (SSP) complex| which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells

the full length nature of some of these variants has not been determined

ITK Polyclonal Antibody, 50ul Cell fragmentation and collection USP45 differs from other USPsThis gene encodes an intracellular tyrosine kinase expressed in T cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T cell proliferation and differentiation.