WFS1 Polyclonal Antibody, 50ul Roller Bottles The activity of the encoded

The activity of the encoded enzyme is enhanced by phosphatidylinositol 4

Related pseudogenes have been identified on chromosomes 4 and 14

Phosphorylation results in the inhibition of transcriptional coactivation through YWHAZ-mediated nuclear export

which is an ubiquitin-conjugating enzyme involved in embryonic development

Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection

WFS1 Polyclonal Antibody, 50ul Roller Bottles The activity of the encodedThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.