Tau(Phospho Ser356) Polyclonal Antibody, 50ul Nucleic Acid Amplification The dimer associates in a

The dimer associates in a DNA-dependent manner with PRKDC to form the DNA-dependent protein kinase complex DNA-PK| and with the LIG4-XRCC4 complex

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C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes

allowing fusion in the presence of calcium

which are subsequently degraded by the 26S proteasome

Tau(Phospho Ser356) Polyclonal Antibody, 50ul Nucleic Acid Amplification The dimer associates in aThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,