LAP2B Polyclonal Antibody, 20ul Custom DNA Oligos Regulates signaling cascades probably through

Regulates signaling cascades probably through protein ubiquitination and/or sequestration

The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain

This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus

The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes

653 bases and maps to human chromosome 2q14

LAP2B Polyclonal Antibody, 20ul Custom DNA Oligos Regulates signaling cascades probably throughalternative products: Additional isoforms seem to exist,Has two structurally independent, non interacting domains: LEM like (also called LAP2 N or LEM D) and LEM (also called LAP2 C or LEM B). LEM like binds DNA while LEM interacts with BANF1.,May be involved in the structural organization of the nucleus and in the post mitotic nuclear assembly. Play an important role, together with LMNA, in the nuclear anchorage of RB1.,May help direct the assembly