EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants encoding different isoforms

This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5

BHLHE41 (basic helix-loop-helix family member e41) encodes a basic helix-loop-helix protein expressed in various tissues

CLCN4 is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I)

Mutations in this gene have been associated with pontocerebellar hypoplasia type 2

EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Alternative splicing of this geneThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.