NFκB-p65(Phospho Ser311) Polyclonal Antibody, 100ul Reservoirs The encoded protein moves between

The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype

Processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) seem not be active

Expression of PMEPA1 is induced by androgens and transforming growth factor beta

The full-length nature of the spliced transcript is not known

NFκB-p65(Phospho Ser311) Polyclonal Antibody, 100ul Reservoirs The encoded protein moves betweenNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four