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EMAL4 Rabbit Polyclonal Antibody, 20ul ADME which are encoded by separate

SKU: 70400346611

4.4
PLN97.20 PLN144.20

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EMAL4 Rabbit Polyclonal Antibody, 20ul ADME which are encoded by separateThis gene is a member of the echinoderm microtubule associated protein like family. The encoded WD repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene which generates EML4 ALK fusion transcripts is one of the primary mutations associated with non small cell lung cancer. Alternative splicing of this gene results in two transcript variants.

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Description

which are encoded by separate genes

with some of them functioning as activators and some as repressors of transcription

this protein lacks the transmembrane domains which are characteristic of most ABC transporters

and thus may mediate the signaling processes that lead to the activation of JAK1

such as mitogenic activation

EMAL4 Rabbit Polyclonal Antibody, 20ul ADME which are encoded by separateThis gene is a member of the echinoderm microtubule associated protein like family. The encoded WD repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene which generates EML4 ALK fusion transcripts is one of the primary mutations associated with non small cell lung cancer. Alternative splicing of this gene results in two transcript variants.

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