ACADV Polyclonal Antibody, 20ul Hepatocytes FAM48A also named as C13orf19

FAM48A also named as C13orf19 or SUPT20H is a 779 amino acid protein

The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation

Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

|Contains 1 MH1 (MAD homology 1) domain

In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

ACADV Polyclonal Antibody, 20ul Hepatocytes FAM48A also named as C13orf19The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta oxidation pathway. This acyl Coenzyme A dehydrogenase is specific to long chain and very long chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding