Karyopherin Alpha2 Polyclonal Antibody, 100ul Gene Editing form a cytokine receptor gene

form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

Members of this family share a common domain structure that consists of a transcription activation domain

This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors

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Karyopherin Alpha2 Polyclonal Antibody, 100ul Gene Editing form a cytokine receptor geneThe import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy independent docking of the protein to the nuclear envelope and the second is an energy dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in