SG196 Rabbit Polyclonal Antibody, 50ul Pipette Filler TBX3 (T-box 3) is a

TBX3 (T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086)

Mutations in this gene are associated with neutrophil immunodeficiency syndrome

This plate is TC treated for enhanced cell growth

Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms

SG196 Rabbit Polyclonal Antibody, 50ul Pipette Filler TBX3 (T-box 3) is aThis gene encodes a protein that may be involved in the presentation of the laminin binding O linked carbohydrate chain of alpha dystroglycan (a DG) which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker Warburg syndrome (WWS) phenotype.