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PEA-15 Polyclonal Antibody, 50ul[BT-AP07046] Mini dry bath Unlike the other cofactors of

SKU: 71006653810

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07046] Mini dry bath Unlike the other cofactors ofPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

Unlike the other cofactors of these protease cascades

This gene encodes a member of the eyes absent (EYA) family of proteins

The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion

Luciferase from the firefly has become one of the more widely used reporter proteins for the study of gene expression

This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans

PEA-15 Polyclonal Antibody, 50ul[BT-AP07046] Mini dry bath Unlike the other cofactors ofPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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