PNKD Polyclonal Antibody, 50ul Recombinant Protein Yeast Maf1 is a negative

Yeast Maf1 is a negative effector of RNA polymerase III (Pol III)

which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain

Because of the conservation of N protein sequence and its strong immunogenicity

Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly

A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation

PNKD Polyclonal Antibody, 50ul Recombinant Protein Yeast Maf1 is a negativeThis gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.