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IKK gamma(Phospho Ser376) Polyclonal Antibody, 20ul In vitro Transcription Deficiency of this enzyme activity

SKU: 71095307535

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IKK gamma(Phospho Ser376) Polyclonal Antibody, 20ul In vitro Transcription Deficiency of this enzyme activityThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria

Demethylation of Lys residue generates formaldehyde and succinate

Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins

It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation

autoimmune diseases and prostate cancer

IKK gamma(Phospho Ser376) Polyclonal Antibody, 20ul In vitro Transcription Deficiency of this enzyme activityThis gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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