SPB6 Polyclonal Antibody, 100ul Serum Two isoforms of CEP55 are

Two isoforms of CEP55 are expressed due to alternative splicing events

The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell

|induction:Highly up-regulated in neuroblastostoma cells by RA treatment inducing neurite outgrowth

All variants share the N-terminal region in common

NBEAL1 is also found at low levels in peripheral blood leukocytes

SPB6 Polyclonal Antibody, 100ul Serum Two isoforms of CEP55 areThe protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov) serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection