ADAM10 Polyclonal Antibody, 50ul PCR Series are located closely on chromosome

are located closely on chromosome 11

This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

Mutations in ROR2 can cause brachydactyly type B

This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells| however

ADAM10 Polyclonal Antibody, 50ul PCR Series are located closely on chromosomeMembers of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. ADAM10 encodes and ADAM family member that cleaves many proteins including TNF alpha and E cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.