TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation It functions as part of

It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters

Pseudogenes of this gene are found on chromosomes 13 and 17

The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1)

amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection

The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo

TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation It functions as part ofThe protein encoded by this gene forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The encoded protein is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.