HLAE Polyclonal Antibody, 50ul Sampling Tubes suggesting its involvement in the

suggesting its involvement in the TP53-dependent regulatory pathway

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation

Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA

|tissue specificity:Expressed at low levels in several tissues| including brain| kidney| lung| prostate| testis| spinal cord| adrenal gland| and trachea

and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12

HLAE Polyclonal Antibody, 50ul Sampling Tubes suggesting its involvement in theHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1