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MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator As a monomer

SKU: 71914629149

4.8
EUR142.00 EUR163.00

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MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator As a monomerMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

Store: avramcheva.com · Domain: avramcheva.com

Description

As a monomer

gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS)

but there is no solid evidence for selenocysteine incorporation (PMID: 12538601)

PIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family

-delta and -epsilon

MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator As a monomerMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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