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p27 Polyclonal Antibody, 50ul[BT-AP06756] Gene Editing Reducing expression of this gene

SKU: 71988561434

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p27 Polyclonal Antibody, 50ul[BT-AP06756] Gene Editing Reducing expression of this geneCDKN1B encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the

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Description

Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation

PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11) encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1

Belongs to the MHC class I family

Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions

MIM 601912) is required for many cellular processes

p27 Polyclonal Antibody, 50ul[BT-AP06756] Gene Editing Reducing expression of this geneCDKN1B encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the

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