Tuberin Polyclonal Antibody, 50ul[BT-AP09285] Cellular Function Assays This receptor transduces signals that

This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK

Alternative splicing of TBX3 results in three transcript variants encoding different isoforms

Related pseudogenes have been identified on chromosomes 3 and 10

the members of the KappaB-Ras subfamily do not contain the conserved Gly and Gln residues in positions 13 and 65

This receptor may provide essential lipids

Tuberin Polyclonal Antibody, 50ul[BT-AP09285] Cellular Function Assays This receptor transduces signals thatMutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.