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KIF20A Polyclonal Antibody, 50ul Human Genome Knockout Libraries Two of the isoforms (A

SKU: 72334606053

4.2
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KIF20A Polyclonal Antibody, 50ul Human Genome Knockout Libraries Two of the isoforms (AMitotic kinesin required for chromosome passenger complex (CPC) mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP) bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end directed motility.

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Description

Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap

The protein features multiple HEAT repeats

This protein associates with the embryonic ectoderm development protein| the VAV1 oncoprotein| and the X-linked nuclear protein

which heterodimerizes with type I keratins to form hair and nails

with each channel holding 3 mL

KIF20A Polyclonal Antibody, 50ul Human Genome Knockout Libraries Two of the isoforms (AMitotic kinesin required for chromosome passenger complex (CPC) mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP) bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end directed motility.

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