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Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ colon and intestine

SKU: 72357214255

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USD123.75 USD171.75

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Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ colon and intestineAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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Description

colon and intestine

This kinase blocks the ubiquitination of tumor suppressor p53

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors

Potassium voltage-gated channel subfamily G member 2 is a gamma subunit of the voltage-gated potassium channel

Expression level and methylation status of this gene may be correlated with bone mineral density

Presenilin 1(Phospho Ser357) Polyclonal Antibody, 100ul CellSafe™ colon and intestineAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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