MYH9 Polyclonal Antibody, 50ul Erlenmeyer Flasks Members of this family are

Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions

whose degradation is induced in a proteasome-dependent manner by MDM2

It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix

May alternatively act as a cellular target for adenovirus E3-14

The encoded protein is associated with angiogenesis| with potential roles in endothelial tube formation and the migration of endothelial cells

MYH9 Polyclonal Antibody, 50ul Erlenmeyer Flasks Members of this family areThis gene encodes a conventional non muscle myosin; this protein should not be confused with the unconventional myosin 9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non syndromic sensorineural deafness