GNRR2 Polyclonal Antibody, 50ul Oligo Pool ATP-binding cassette sub-family G member

ATP-binding cassette sub-family G member 1 encoded by ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters

It is also cleaved by caspase-3 in vitro

The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

Alternative splicing of this gene produces multiple transcript variants| some encoding different isoforms

GNRR2 Polyclonal Antibody, 50ul Oligo Pool ATP-binding cassette sub-family G memberIn non hominoid primates and non mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven transmembrane G protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs