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4E-BP1(Phospho-Thr37/46) Rabbit Polyclonal Antibody, 20ul Transporters Contains 1 Ras-GEF domain

SKU: 72672843223

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4E-BP1(Phospho-Thr37/46) Rabbit Polyclonal Antibody, 20ul Transporters Contains 1 Ras-GEF domainThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

Contains 1 Ras-GEF domain

which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP)

With a specialized treatment

Mutations in the gene cause Sjogren-Larsson syndrome

The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation

4E-BP1(Phospho-Thr37/46) Rabbit Polyclonal Antibody, 20ul Transporters Contains 1 Ras-GEF domainThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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