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Mouse Dihydrofolate Reductase, DHFR ELISA Kit, 96T Cell Culture Plates This protein contains two conserved

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Mouse Dihydrofolate Reductase, DHFR ELISA Kit, 96T Cell Culture Plates This protein contains two conservedKey enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (PubMed: 25980602). Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (PubMed: 25980602). Binds its own mRNA.

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Description

This protein contains two conserved domains| an N-terminal RUN domain and a C-terminal DUF4206 domain

an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains

ABC proteins transport various molecules across extra- and intra-cellular membranes

P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes

MAPK1/ERK2 and AKT1 (By similarity)

Mouse Dihydrofolate Reductase, DHFR ELISA Kit, 96T Cell Culture Plates This protein contains two conservedKey enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (PubMed: 25980602). Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (PubMed: 25980602). Binds its own mRNA.

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