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GFR Alpha-4 Polyclonal Antibody, 20ul Transporters CLEC4A (C-type lectin domain family

SKU: 7274381657

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GFR Alpha-4 Polyclonal Antibody, 20ul Transporters CLEC4A (C-type lectin domain familyThe protein encoded by GFRA4 (GDNF family receptor alpha 4)is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. GFRA4 is a candidate gene for RET associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4.

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Description

CLEC4A (C-type lectin domain family 4 member A) encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily

Defects in ITGA7 are associated with congenital myopathy

and MMP13) and support different biological activities such as cell proliferation

They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine

It is a cytoskeletal protein that interacts with F-actin and Arp2/3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics

GFR Alpha-4 Polyclonal Antibody, 20ul Transporters CLEC4A (C-type lectin domain familyThe protein encoded by GFRA4 (GDNF family receptor alpha 4)is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. GFRA4 is a candidate gene for RET associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4.

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