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GRASP Polyclonal Antibody, 100ul[BT-AP15777] Cryopreservation Three major isoforms of Bim

SKU: 72843329416

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GRASP Polyclonal Antibody, 100ul[BT-AP15777] Cryopreservation Three major isoforms of BimThis gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C terminal PDZ binding motif. Alternately spliced transcript variants have been observed for this gene.

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Description

Three major isoforms of Bim are generated by alternative splicing: bimEL

Multiple transcript variants encoding different isoforms have been found for SIRPB1

Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response

and it occurs only in absence of calcium

-1B and -1D

GRASP Polyclonal Antibody, 100ul[BT-AP15777] Cryopreservation Three major isoforms of BimThis gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C terminal PDZ binding motif. Alternately spliced transcript variants have been observed for this gene.

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