NuMA(Phospho-Ser395) Rabbit Polyclonal Antibody, 50ul Stepper Surfeit locus protein 1 is

Surfeit locus protein 1 is a member of the SURF1 family

whereby some individuals have a functional allele that encodes a full-length protein

which is located 10 kb downstream from this gene

Control of centriole number is therefore crucial for genome stability and embryogenesis

This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias

NuMA(Phospho-Ser395) Rabbit Polyclonal Antibody, 50ul Stepper Surfeit locus protein 1 isThis gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple