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L-type Ca++ CP gamma5 Polyclonal Antibody, 20ul Polyclonal Antibodies The tumor necrosis factor superfamily

SKU: 72904190440

4.4
PLN111.00 PLN151.00

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L-type Ca++ CP gamma5 Polyclonal Antibody, 20ul Polyclonal Antibodies The tumor necrosis factor superfamilyThe protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight member protein subfamily of the PMP 22 EMP MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar

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Description

The tumor necrosis factor superfamily member 4 functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

Accumulation of EXPAND1/MUM1 at damaged DNA sites is thought to modify the structure of the chromatin and allow access to other DNA repair factors

and plays a regulatory role in Fas-mediated apoptosis

The protein interacts with γ-tubulin through its coiled coil domains to localize at the centrosome

There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites

L-type Ca++ CP gamma5 Polyclonal Antibody, 20ul Polyclonal Antibodies The tumor necrosis factor superfamilyThe protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight member protein subfamily of the PMP 22 EMP MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar

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