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MACC1 Polyclonal Antibody, 20ul Live Cell Imaging it is overexpressed in gynecological

SKU: 73095491753

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MACC1 Polyclonal Antibody, 20ul Live Cell Imaging it is overexpressed in gynecologicalMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis free survival (Stein et al. 2009 [PubMed: 19098908]).

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Description

it is overexpressed in gynecological tumor samples

It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin

COL12A1 encodes the alpha chain of type XII collagen

characterized by a zinc finger-like structural motif

Cyclin D1 encoded by CCND1 belongs to the highly conserved cyclin family

MACC1 Polyclonal Antibody, 20ul Live Cell Imaging it is overexpressed in gynecologicalMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis free survival (Stein et al. 2009 [PubMed: 19098908]).

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