MAGI-2 Polyclonal Antibody, 50ul DNA Synthesis ACYP2 (acylphosphatase 2) encodes the

ACYP2 (acylphosphatase 2) encodes the muscle-type isoform (MT)

Composed of three domains: a modulating N-terminal domain| a DNA-binding domain and a C-terminal steroid-binding domain

Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata

The DNA-binding activity may reside exclusively on the 70 kDa subunit

Contains 2 RING-type zinc fingers

MAGI-2 Polyclonal Antibody, 50ul DNA Synthesis ACYP2 (acylphosphatase 2) encodes theThe protein encoded by MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)interacts with atrophin 1. Atrophin 1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase like domain, and multiple PDZ domains. It has structural similarity to the membrane associated guanylate kinase homologue (MAGUK)