Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 20ul[BT-AP04537] Serological Pipets Studies of the rat homolog

Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection

and an ATPase domain

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0

and downregulation of this gene may play a role in breast cancer

Methylation of the genes promoter has been associated with several cancer types

Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 20ul[BT-AP04537] Serological Pipets Studies of the rat homologThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase