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VE-Cadherin Polyclonal Antibody, 50ul[BT-AP15453] In vitro Assessment Mutations in this gene are

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VE-Cadherin Polyclonal Antibody, 50ul[BT-AP15453] In vitro Assessment Mutations in this gene areThis gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a

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Description

Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome

Mixed lineage kinase domain-like protein contains a protein kinase-like domain

The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway

The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice

which may contribute to many overlapping functions of this cytokine and IL13

VE-Cadherin Polyclonal Antibody, 50ul[BT-AP15453] In vitro Assessment Mutations in this gene areThis gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a

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