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GFRA3 Polyclonal Antibody, 100ul Primary Antibodies The 5' UTR of some

SKU: 7387478994

4.6
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GFRA3 Polyclonal Antibody, 100ul Primary Antibodies The 5' UTR of someThe protein encoded by this gene is a glycosylphosphatidylinositol(GPI) linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.

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Description

The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12

a functional arg-gly-asp cell attachment sequence

The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme

which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade

The N-terminus is composed of the phosphotyrosine binding (PTB) domain

GFRA3 Polyclonal Antibody, 100ul Primary Antibodies The 5' UTR of someThe protein encoded by this gene is a glycosylphosphatidylinositol(GPI) linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.

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