PLC Gamma2 Polyclonal Antibody, 100ul[BT-AP07263] Digital Burette APC encodes a tumor suppressor

APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway

Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor

have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome

and downstream products

Mutations have been associated with some forms of Zellweger syndrome| a heterogeneous group of peroxisome assembly disorders

PLC Gamma2 Polyclonal Antibody, 100ul[BT-AP07263] Digital Burette APC encodes a tumor suppressorThe protein encoded by PLCG2 (phospholipase C gamma 2) is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in PLCG2 have