SPRE3 Rabbit Polyclonal Antibody, 100ul Site-directed Mutagenesis Many G protein receptors serve

Many G protein receptors serve as targets for pharmaceutical drugs

Three transcript variants encoding two different isoforms have been found for POLR2E

This protein (BCL2 associated athanogene 4) was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3)

These two polypeptides share 66% amino acid sequence identity

Pseudogenes corresponding to MRPL49 (mitochondrial ribosomal protein L49)are found on chromosomes 5q and 8p

SPRE3 Rabbit Polyclonal Antibody, 100ul Site-directed Mutagenesis Many G protein receptors serveThis gene encodes a protein with a C terminal Sprouty like cysteine rich domain (SRY) and an N terminal Ena Vasodilator stimulated phosphoprotein (VASP) homology 1 (EVH 1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen activated protein (MAP) kinase signaling particularly during organogenesis. Alternative splicing results in multiple transcript variants.