DNA Ligase IV Polyclonal Antibody, 20ul[BT-AP02654] Multi-Layer Cell Culture System due to defective mitochondrial and

due to defective mitochondrial and peroxisomal fission (EMPF)

oocyte and bone tissue development

Multiple transcript variants encoding different isoforms have been found for CLK1

GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity

Mutations in BRCA1 are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

DNA Ligase IV Polyclonal Antibody, 20ul[BT-AP02654] Multi-Layer Cell Culture System due to defective mitochondrial andDNA ligase 4 encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and