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Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) don't wait

SKU: 7407237736

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Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) don't waitSerine threonine protein kinase involved in transcription regulation, p53 TP53 mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1 Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53 TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53

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Description

don't wait

Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role

The encoded protein contains 17 leucine-rich repeats and one PDZ domain

Mutations in this gene result in persistent Mullerian duct syndrome

The encoded protein has been shown to be capable of interacting with several GPCRs

Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) don't waitSerine threonine protein kinase involved in transcription regulation, p53 TP53 mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1 Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53 TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53

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