FoxC1/2 Polyclonal Antibody, 50ul ADME and the C-terminal domain has

and the C-terminal domain has IMP cyclohydrolase activity

The encoded protein likely acts as a heterodimer with another bHLH protein

a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions

a heterodimer of importin alpha and beta subunits also known as karyopherins

which is a common gamma chain shared by the receptors of various cytokines

FoxC1/2 Polyclonal Antibody, 50ul ADME and the C-terminal domain hasFOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld Rieger