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c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 20ul Apoptosis & Autophagy BAGE2 is a candidate gene

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c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 20ul Apoptosis & Autophagy BAGE2 is a candidate geneThis gene is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated substrates and

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Description

BAGE2 is a candidate gene encoding tumor antigens

suggesting it may have a role in spermatogenesis

The protein encoded by this gene is a subunit of the receptor for IL23A/IL23

These proteins are characterized by the presence of seven alpha-helical transmembrane domains

but not the GoLoco 2 domain

c-Cbl(Phospho-Tyr731) Rabbit Polyclonal Antibody, 20ul Apoptosis & Autophagy BAGE2 is a candidate geneThis gene is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated substrates and

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