AVR2B Polyclonal Antibody, 20ul Immunology Proteins of this family are

Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus

The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins)

It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein

Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4

Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities

AVR2B Polyclonal Antibody, 20ul Immunology Proteins of this family areActivins are dimeric growth and differentiation factors which belong to the transforming growth factor beta (TGF beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand binding extracellular domain with cysteine rich