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Rb Polyclonal Antibody, 100ul[BT-AP07690] Microplate Mixer The protein localizes to cytoplasmic

SKU: 7441299945

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Rb Polyclonal Antibody, 100ul[BT-AP07690] Microplate Mixer The protein localizes to cytoplasmicThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

The protein localizes to cytoplasmic filaments

The protein encoded by this gene is a member of the STAT protein family

PTM:Ubiquitinated

The encoded protein is active in bulk vitamin C transport involving epithelial surfaces

Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom

Rb Polyclonal Antibody, 100ul[BT-AP07690] Microplate Mixer The protein localizes to cytoplasmicThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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