Gab 2 Polyclonal Antibody, 100ul[BT-AP03409] Mechanical Pipette A similar protein in rat

A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes

a component of the mitogen-activated protein kinase pathway

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suggesting a role in the regulation of DNA replication

Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression

Gab 2 Polyclonal Antibody, 100ul[BT-AP03409] Mechanical Pipette A similar protein in ratGAB2 is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. GRB2 associated binding protein 2 encoded by GAB2 is the principal activator of phosphatidylinositol 3