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CD141 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This gene encodes a protein

SKU: 74447293215

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CD141 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This gene encodes a proteinThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

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Description

This gene encodes a protein that is a member of the CXC subfamily of chemokines

The T-box family members share a common DNA binding domain

|PTM:Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1| export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration

developmental stage:Expressed throughout the cell cycle

The encoded protein may be involved in endocytic sorting

CD141 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This gene encodes a proteinThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

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