ARHGEF9 Polyclonal Antibody, 100ul Funnels The canonical alpha isoform of

The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system

The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal

plates×8pcs

The protein localizes to the nucleoli and interacts with the U3 snoRNP complex

IRF1 also functions as a transcription activator of genes induced by interferons alpha

ARHGEF9 Polyclonal Antibody, 100ul Funnels The canonical alpha isoform ofThe Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho like GTPase that switches between the active (GTP bound) state and inactive (GDP bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.