IP3 Receptor(Phospho-Ser1756) Rabbit Polyclonal Antibody, 50ul Stepper the protein encoded by TSPO

the protein encoded by TSPO (translocator protein) interacts with some benzodiazepines and has different affinities than its endogenous counterpart

This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes

This protein contains an I domain

High levels also detected in liver

Mutations in this gene have been associated with hereditary hemochromatosis type III

IP3 Receptor(Phospho-Ser1756) Rabbit Polyclonal Antibody, 50ul Stepper the protein encoded by TSPOThis gene encodes an intracellular receptor for inositol 1 4 5 trisphosphate. Upon stimulation by inositol 1 4 5 trisphosphate this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15 a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.