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SPT16 Polyclonal Antibody, 100ul Modified Oligos RCC1 is dynamically chromatin-bound throughout

SKU: 74518684230

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SPT16 Polyclonal Antibody, 100ul Modified Oligos RCC1 is dynamically chromatin-bound throughoutTranscription of protein coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A H2B to effect nucleosome disassembly and transcription elongation. FACT is

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Description

RCC1 is dynamically chromatin-bound throughout the cell cycle

The extracellular region possesses a lengthy Pro‑rich region (aa 55‑200)

In young patients suffering from acute lymphoblastic leukemia (ALL)

Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene

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SPT16 Polyclonal Antibody, 100ul Modified Oligos RCC1 is dynamically chromatin-bound throughoutTranscription of protein coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A H2B to effect nucleosome disassembly and transcription elongation. FACT is

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