p70 S6 Kinase beta(Phospho Ser423) Polyclonal Antibody, 100ul Sample Library Tubes The type I keratin genes

The type I keratin genes are clustered in a region of chromosome 17q12-q21

Yeast Maf1 is a negative effector of RNA polymerase III (Pol III)

The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E)| which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs

These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them

is a 471 amino acid protein that contains one FYVE-type zinc finger

p70 S6 Kinase beta(Phospho Ser423) Polyclonal Antibody, 100ul Sample Library Tubes The type I keratin genesThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.